Intermittent fasting: return to cancer-risk foods

US study: nutrition is a separate phase that requires a lot of attention

called”intermittent fasting” and quickly asserted itself “fad” dietafter experience, in various forms announced by many VIPs and influencers.
Among them are entrepreneur Elon Musk (who apparently lost 9 kg this way) and former British Prime Minister Rishi Sunak (who adopted the 36-hour abstinence version), actress Jennifer Aniston and immunologist Antonella Viola (16 years old for them). :8 formula, concentrating food consumption for 8 hours a day) and model Gisele Bunchen (follower of 5:2, i.e. 5 normal days and 2 fasting days: the first modern intermittent fasting popularized by Michael Mosley in 2012).

And me advantages are recognizedeven at the scientific level. “There have been fasting regimes for more than a century improved health, longevity and rtissue generation in a variety of organisms, including humans,” says the Boston MIT study.
But before adding disturbing news: “Post-fasting feeding increases intestinal stem cell (ISC) proliferation and tumor formation“.

Gentle nutrition after fasting

For the first time in their study, “Nutrition after short-term fasting improves intestinal stemness via polyamines,” the researchers looked specifically at how fasting and post-fasting nutrition affects adult stem cells and tumorigenesis. .
Thus, it turned out that in order to determine “higher incidence of tumors in the small intestine and colon technically compared to fasting or ad libitum feeding situations in the post-fasting feeding phaseIncreased regenerative capacity of Lgr5+ Iscs and loss of Apc tumor suppressor gene in post-fasting Iscs“. And this, they explain, “post-fasting nutrition is a different situation.”

“In the light of our results – the conclusion of the MIT team – i Fast feeding cycles should be carefully considered and tested While planning diet-based strategies for regeneration without increasing cancer risk, rapid nutrition induces stem cell-driven regeneration and tumorigenesis.

Intermittent fasting: how to behave

From the comparison between them 3 groups of mice (1 person fasted for 24 hours, 1 person continued to eat regularly, and 1 person was allowed to eat anything after fasting), the researchers noted that the stage of stem cell regeneration where most cancer mutations occuractivated At the end of the 24-hour refeeding periodwas found to be more active with intestinal stem cells than non-fasting mice.
To be clear, fasting should not be demonized based on these new findings. Also because the results include, among the health benefits associated with it tissue renewal and rejuvenationthe reducing inflammation (underlying many modern chronic diseases) and insulin resistancewhich can lead to the onset of diabetes.

While avoiding “do-it-yourself” as is generally recommended for all medical practices, the findings in Boston suggest more pay maximum attention to the feeding phase, especially avoid drinks as soon as he started feeding again. Fasting, in other words, does not justify eating whatever you want during the non-observant phases.

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